Description: Description Dutch: Stroomkabel; Description French: Câble électrique

Description: Description Dutch: MC-11 Elektrische labelopwikkelaar voor het Verenigd Koninkrijk; Description French: Enrouleur d’étiquettes MC-11 pour le Royaume-Uni

Description: Description Dutch: LD-100-RS Automatische labeldispenser voor het Verenigd Koninkrijk; Description French: Distributeur automatique d’étiquettes LD-100-RS pour le Royaume-Uni

Description: SARS-CoV-2 (COVID-19) Alpha Variant (B.1.1.7, UK) Spike P681H Peptide

Description: SARS-CoV-2 full-length Trimeric Spike Antigen (UK/Nigerian Variant, 100ug)

Description: SARS-CoV-2 full-length Trimeric Spike Antigen (UK/Nigerian Variant, 1mg)

Description: SARS-CoV-2 full-length Trimeric Spike Antigen (UK/Nigerian Variant, 10mg)

Description: A new variant of SARS-CoV-2 is spreading in the UK and is rapidly becoming a global threat. It ischaracterized by multiple mutations in the spike protein. Among them, N501Y is of major concernbecause it involves one of the six key amino acid residues determining a tight interaction of theSARS-CoV-2 receptor-binding domain (RBD) with its cellular receptor angiotensin-converting enzyme2 (ACE2).

Description: All viruses undergo fast mutations and adept quickly to the countermeasures that the immune systems creates against them. SARS-CoV-2 of the COVID-19 pandemic is no exception here. During the pandemic multiple mutant strains arose. To help the science combat these mutants ProSci offers the RB-Domains of these mutant SPIKE proteins. That is the full RBD domain of the SPIKE surface protein SARS-CoV-2 of the mutant strain B.1.1.7, also commonly known as the "UK / Great Britain mutant".

Description: All viruses undergo fast mutations and adapt quickly to the countermeasures that the immune systems creates. SARS-CoV-2 of the COVID-19 pandemic is no exception to this. During the pandemic multiple mutant strains arose. To help the sciencific community to combat these mutants ProSci offers the SPIKE protein of the mutants in full-length and active in their native trimeric form, stabilized with the LMNG detergent. This is the SPIKE protein of the mutant strain B.1.525.

Description: SARS-CoV-2 shares 79.5% sequence identity with SARS-CoV and is 96.2% identical at the genome level to the bat coronavirus BatCoV RaTG133, suggesting it had originated in bats. The coronaviral genome encodes four major structural proteins: the Spike (S) protein, Nucleocapsid (N) protein, Membrane/Matrix (M) protein and the Envelope (E) protein. The SARS Envelope (E) protein contains a short palindromic transmembrane helical hairpin that seems to deform lipid bilayers, which may explain its role in viral budding and virion envelope morphogenesis. The SARS Membrane/Matrix (M) protein is one of the major structural viral proteins. It is an integral membrane protein involved in the budding of the viral particles and interacts with SARS Spike (S) protein and the Nucleocapsid (N) protein. The N protein contains two domains, both of them bind the virus RNA genome via different mechanisms.The CoV Spike (S) protein assembles as trimer and plays the most important role in viral attachment, fusion and entry. It is composed of a short intracellular tail, a transmembrane anchor and a large ectodomain that consists of a receptor binding S1 subunit (RBD domain) and a membrane-fusing S2 subunit. The S1 subunit contains a receptor binding domain (RBD), which binds to the cell surface receptor angiotensin-converting enzyme 2 (ACE2) present at the surface of epithelial cells. Recently, a more transmissible variant of SARS-CoV-2, called B.1.1.7, was detected in the south of England. This variant carries a mutation in the RBD at the position 501 (N501Y).

Description: SARS-CoV-2 shares 79.5% sequence identity with SARS-CoV and is 96.2% identical at the genome level to the bat coronavirus BatCoV RaTG133, suggesting it had originated in bats. The coronaviral genome encodes four major structural proteins: the Spike (S) protein, Nucleocapsid (N) protein, Membrane/Matrix (M) protein and the Envelope (E) protein. The SARS Envelope (E) protein contains a short palindromic transmembrane helical hairpin that seems to deform lipid bilayers, which may explain its role in viral budding and virion envelope morphogenesis. The SARS Membrane/Matrix (M) protein is one of the major structural viral proteins. It is an integral membrane protein involved in the budding of the viral particles and interacts with SARS Spike (S) protein and the Nucleocapsid (N) protein. The N protein contains two domains, both of them bind the virus RNA genome via different mechanisms.The CoV Spike (S) protein assembles as trimer and plays the most important role in viral attachment, fusion and entry. It is composed of a short intracellular tail, a transmembrane anchor and a large ectodomain that consists of a receptor binding S1 subunit (RBD domain) and a membrane-fusing S2 subunit. The S1 subunit contains a receptor binding domain (RBD), which binds to the cell surface receptor angiotensin-converting enzyme 2 (ACE2) present at the surface of epithelial cells. Recently, a more transmissible variant of SARS-CoV-2, called B.1.1.7, was detected in the south of England. This variant carries a mutation in the RBD at the position 501 (N501Y).The SARS-CoV-2 Spike Protein S1 (RBD) (rec.) (His) (B.1.1.7 Variant, UK) can be used as antigen in Serological ELISA Kits to detect anti-SARS-CoV-2 Spike (RBD) antibodies in serum or plasma.

Description: All viruses undergo fast mutations and adapt quickly to the countermeasures that the immune systems creates. SARS-CoV-2 of the COVID-19 pandemic is no exception to this. During the pandemic multiple mutant strains arose. To help the sciencific community to combat these mutants ProSci offers the SPIKE protein of the mutants in full-length and active in their native trimeric form, stabilized with the LMNG detergent.; This is the spike protein of the mutant strain B.1.1.7, also commonly known as the "UK / Great Britain mutant".